Panettone Panini with Prosciutto and Mozzarella


Fruitcake isn’t typically high on my holiday wishlist, but after trying out today’s Panettone Panini with Prosciutto and Mozzarella I think that may have to change.

I was first introduced to panettone, the Italian fruitcake, around this time last year when I interviewed Martha Stewart’s executive director of food and entertaining, Lucinda Scala Quinn on my other blog, Cooking On the Side. Among the many ideas Lucinda offered for serving panettone was an off-the-cuff suggestion of making panini out of it with prosciutto and mozzarella. I waited all year for the next holiday season to come around to give this unique combination a try.

If someone gave you a fruitcake for Christmas this year, you’ve got to try this. The sweet candied fruits in the panettone just love being paired with the salty prosciutto. It’s an absolute flavor blast, I loved it. These sandwiches would probably be just as good cold, but if you grill them you get the benefit of that nice stretchy mozzarella in the middle. I definitely have a newfound appreciation for fruitcake!

Panettone Panini with Prosciutto and Mozzarella


Panettone Panini with Prosciutto and Mozzarella

Prep time: 10 minutes | Cook time: 8 minutes | Total time: 18 minutes

Yield: 4 panini


  • 1/2 (17.5 ounce) panettone sliced into 1/2-inch thick rounds*
  • 4 ounces sliced prosciutto
  • 8 ounces sliced water-packed fresh mozzarella, patted dry


  1. Preheat the panini grill to medium high heat.
  2. For each sandwich: Cut a slice of panettone down the middle to create top and bottom semi-circle halves. Lay 1/4 of the prosciutto on one panettone half. Top the prosciutto with two or three slices of cheese. Close the sandwich with the other panettone half.
  3. Grill the panini until the cheese is melted and the panettone is toasted, 3 to 4 minutes.

* You typically might serve a panettone in wedge slices but for making sandwiches, which require slices of even thickness, I recommend cutting the loaf crosswise into 1/2-inch thick rounds.


KathyPanini Happy, online since 2008, is more than just a sandwich blog. Here, you'll find hundreds of my original panini recipes, my guide to choosing a panini press and a whole lot of other creative uses for the panini press.
~ Kathy Strahs
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  1. Kathy, This is shear genius!

    Posted 12.19.11 Reply
  2. After eating panettone in a sweet trifle, this is a great way to see it used with a savory twist.

    Posted 12.19.11 Reply
  3. Jeanette wrote:

    What a fun idea – I imagine the sweetness of the panettone would compliment the saltiness of the prosciutto perfectly.

    Posted 12.20.11 Reply
  4. Marla wrote:

    Such an interesting way to use panettone. Love the sweet/savory combo. Happy new year 🙂

    Posted 1.1.12 Reply
  5. Joe wrote:

    Very nice blog. I just got a panini press for Christmas so I am looking for some new tips and recipes. I will check back often.

    Posted 1.18.12 Reply